<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>emergentresearch</PublisherName> <JournalTitle>Emergent Life Sciences Research</JournalTitle> <PISSN>2395-6658 (</PISSN> <EISSN>) 2395-664X (Print)</EISSN> <Volume-Issue/> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season/> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>Research Article</ArticleType> <ArticleTitle>Assessment of in vitro Anti-urolithiatic Potential of Berberis Aristata DC.</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>0</FirstPage> <LastPage>0</LastPage> <AuthorList> <Author> <FirstName>Sonu</FirstName> <LastName>Ambwani</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Urolithiasis is a highly prevalent and excruciating urological condition characterized by the accumulation of stones within the urinary system's walls. Kidney stones, also referred to as nephrolithiasis, urolithiasis, or ureterolithiasis, are classified based on their specific location within the urinary system. Traditional approaches to managing urolithiasis include allopathic medications, surgical interventions and shockwave lithotripsy, all of which are associated with various side effects. Due to these associated drawbacks, there is a growing interest in exploring natural remedies for both the prevention and treatment of urolithiasis. Anti-urolithiatic activity encompasses the capacity of specific plants and their extracts to prevent or alleviate urolithiasis, commonly known as kidney stones. Throughout various cultures, numerous plants have traditionally been employed as natural interventions to ward off or address kidney stones. One such potential herbal plant for management of urolithiasis is Berberis aristata (Indian barberry or Tree Turmeric) which is known for its use in management of urolithiasis in folk medicine. This plant is notably rich in alkaloids, with berberine being the primary alkaloid responsible for its antioxidant and anti-inflammatory properties. In the present in vitro study, aqueous root extract of Berberis aristata (BAE) at varying concentrations was examined for its efficacy on inhibiting the crystallization of calcium oxalate crystals when introduced alongside the extract. The results revealed effectiveness of the extract in preventing crystallization, suggesting its potential utility in managing urinary stone formation. Nevertheless, further investigation is required, particularly in suitable in vivo models, to comprehensively assess the anti-urolithiatic activity of Berberis aristata.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Berberis aristata; Root extract; Urolithiasis; Simultaneous flow static model; In vitro anti-urolithiatic Assays</Keywords> <URLs> <Abstract>https://emergentresearch.org/ubijournal-v1copy/journals/abstract.php?article_id=14999&title=Assessment of in vitro Anti-urolithiatic Potential of Berberis Aristata DC.</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References/> </References> </Journal> </Article> </ArticleSet>