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    <Journal>
      <PublisherName>emergentresearch</PublisherName>
      <JournalTitle>Emergent Life Sciences Research</JournalTitle>
      <PISSN>2395-6658 (</PISSN>
      <EISSN>) 2395-664X (Print)</EISSN>
      <Volume-Issue>Online First</Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>for coming issue</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>2026</Year>
        <Month>02</Month>
        <Day>24</Day>
      </PubDate>
      <ArticleType>Review Article</ArticleType>
      <ArticleTitle>The science of intermittent fasting: Mechanisms and health effects</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>1</FirstPage>
      <LastPage>10</LastPage>
      <AuthorList>
        <Author>
          <FirstName>Himani</FirstName>
          <LastName>Belwal</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Sandhya</FirstName>
          <LastName>Dhyani</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>In recent years, life has gradually shifted towards a more sedentary and convenient lifestyle. This shift is one of the major contributing factors for widespread health related problems. The World Health Organization (WHO) also highlights the global increase in non-communicable and metabolic disorders in the world. This is largely attributed to unhealthy dietary intake, sedentary lifestyle, lack of physical activity etc. One of the major health problems is obesity and overweight, which is no longer confined to high-income countries, but low-income and middle-income countries are also experiencing the same trend.&#13;
&#13;
Intermittent Fasting (IF) is emerging as one promising strategy for weight management and overall health. Intermittent fasting can be done in many ways, like Intermittent Energy Restriction (IER) and Time-Restricted Fasting (TRF). There are various animal and human studies suggesting that Time-Restricted Fasting (TRF) has more pronounced health benefits. The results depicted weight loss, increased insulin sensitivity, improved cognitive function, a change in gut microbe composition, tissue repair, and reduced oxidative stress and inflammatory markers.&#13;
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These effects are the result of key biological mechanisms of Intermittent Fasting (IF) such as metabolic switching of glucose to fat, modulated circadian rhythm pattern, and gut-brain axis. In various studies, it is claimed that intermittent fasting in combination with continuous energy restriction was found to mask the independent effect of intermittent fasting. According to various studies, intermittent fasting alone has the potential to reduce weight and other metabolic problems. Most of the studies are based on animal models and need more data related to human trials. This narrative review explains the evidence based underlying mechanisms of intermittent fasting along with its various health benefits.</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>gut brain axis, insulin-sensitivity, metabolic diseases, non-communicable diseases, obesity</Keywords>
      <URLs>
        <Abstract>https://emergentresearch.org/ubijournal-v1copy/journals/abstract.php?article_id=16150&amp;title=The science of intermittent fasting: Mechanisms and health effects</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
        <References/>
      </References>
    </Journal>
  </Article>
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